Prenatal supplements largely don’t contain the advisable amount of omega-3 fatty acids to forestall premature birth, recent research finds

Most prenatal supplements lack the quantity of omega-3 fatty acids that would help prevent premature birth, i.e. delivery before 37 weeks of pregnancy. That is a Key finding of a brand new studypublished by my team, within the American Journal of Perinatology.

Omega-3 fatty acids are essential nutrients that are mainly present in fatty fish. They help prevent inflammation and thus reduce the danger of premature birth.

However, our study showed that roughly one in six pregnancy supplements containing omega-3 fatty acids available in the marketplace within the United States provide the quantity most pregnant women need.

My colleagues and I used information from the US Department of Agriculture Database of dietary complement labels to discover prenatal supplements that contained omega-3 fatty acids. We then compared the quantity of omega-3 fatty acids listed on the product labels with that recommended amounts in the brand new guidelines published within the American Journal of Obstetrics and Gynecology Maternal-Fetal Medicine by a team of experts representing international obstetric and child health organizations.

The guidelines recommend different dosages of omega-3 fatty acids depending on whether a lady's baseline intake before pregnancy was sufficient or inadequate.

We found that 70% of prenatal supplements containing omega-3 fatty acids provided the quantity advisable for ladies to devour adequately. However, previous research has shown that only 5% of pregnant women and ladies of childbearing age Consume enough omega-3 fatty acids. Therefore, prenatal supplementation with the next amount of omega-3 fatty acids can be helpful for ladies with inadequate intake.

Torso of a pregnant woman holding a glass of water in one hand and vitamins in the other.
Most prenatal vitamins available in the marketplace within the United States don’t contain enough omega-3 fatty acids.
Andersen Ross Photography Inc./DigitalVision via Getty Images

Why it matters

Premature birth is the most important reason behind this Child mortality worldwide. It can be probably the most common reason behind childhood illnesses, resulting in costly hospital stays Neonatal intensive care units. And then there's the hard part emotional toll that it impacts parents and families.

Premature birth also increases a baby's risk of long-term health consequences reminiscent of: mental disabilitychronic illnesses reminiscent of hypertension, diabetes and psychiatric illnesses in maturity.

And yet there are some few treatment options for premature births.

This is where omega-3 fatty acids come into play. They reduce the danger of premature birth by reducing the production of those fatty acids Signaling molecules that trigger labor.

A Cochrane review of 26 randomized controlled trials showed that 1,000 milligrams of additional omega-3 fatty acids per day can reduce the danger of preterm birth by 11% and the danger of early preterm birth (delivery before 34 weeks of pregnancy) by 42%.

Considering that prenatal supplements often don’t contain the required amount of omega-3 fatty acids, one option is to easily take a further omega-3 complement along with a prenatal vitamin to make up the difference and get the profit.

However, omega-3 supplements will not be all the time mandatory. The recent guidelines recommend that every one women of childbearing age devour 250 milligrams of omega-3 fatty acids per day. This amount may be obtained from about two 3-ounce servings per week of fatty fish reminiscent of salmon, mackerel, herring, sardines and anchovies.

If women increase their intake of omega-3 fatty acids before pregnancy, the advisable intake levels while pregnant are lower. This is one option to eliminate the necessity for supplements in the primary place.

However, because of this, women of childbearing age also need to think about the mercury content in fish negative effects on the neurological development of the fetus. While most forms of salmon are low in mercury, certain fish wealthy in omega-3 fatty acids could also be moderately high mercury content. It is significant to seek the advice of local health guidelines regarding mercury levels in fish to make sure secure consumption levels.

What will not be yet known

Omega-3 fatty acids are chemically unstable molecules that are inherently fragile and subsequently prone to oxidation, a process during which oxygen breaks down the molecule and renders it ineffective. Studies have shown large variation within the oxidation states In commercial omega-3 supplements. Worse still, there are few predictors of the standard of omega-3 supplements.

However, despite their high risk of oxidation, commercially available omega-3 supplements have shown an increased risk of oxidation proven advantages in clinical trials.

What's next?

Considering the inconsistent amounts of omega-3 fatty acids in prenatal supplements, their instability, and the likelihood that pre-pregnancy dietary sources offset complement needs, further research is required to grasp how increased omega-3 intake helps Women of childbearing age may be motivated.

Given that many ladies proceed to require omega-3 fatty acids from supplements, longitudinal studies to watch omega-3 levels in prenatal supplements will probably be critical.

Furthermore, ongoing efforts are needed to advertise the implementation of this information in clinical settings to make sure that pregnant women and the health care professionals who look after them can make the most of the good potential of omega-3 fatty acids in pregnancy prevention of preterm birth.

image credit : theconversation.com